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• Lyme Disease in Dogs

  The bacterium that causes Lyme disease can be transmitted to dogs through the bite of an infected tick, most commonly the deer tick (black-legged tick), which is found in the midwestern and eastern United States and throughout Canada. The disease typically causes pain and swelling in the affected dog's joints along with decreased appetite and fever. The kidneys are sometimes affected, in which case the disease is often fatal. Diagnostic testing, treatment, and ways to prevent Lyme disease in your dog, including instructions for tick removal, are explained in this handout.

• Metronidazole

  Metronidazole is given by mouth or injection and is used off-label to treat certain anaerobic bacterial and protozoal infections and gastrointestinal conditions in dogs, cats, and other animals. Give as directed. Side effects may include nausea, vomiting, diarrhea, regurgitation, decreased appetite, tiredness, and drooling. Do not use in pets that are allergic to it, are debilitated, or are pregnant or nursing. If a negative reaction occurs, contact your veterinarian.

• Milbemycin Oxime + Afoxolaner

  Milbemycin oxime + afoxolaner is a heartworm disease preventive that also treats certain internal parasites and controls fleas and ticks in dogs. It is also used off-label to treat mite infestations in dogs. This combination drug is given by mouth as a flavored chew tablet. Certain dog breeds are more sensitive to milbemycin oxime than others; your veterinarian will advise you on the safety of milbemycin oxime use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

• Milbemycin Oxime + Lufenuron

  Milbemycin oxime + lufenuron is a heartworm disease preventive that also treats internal parasites (e.g., whipworms, hookworms, and roundworms) and controls flea populations in dogs. Milbemycin oxime + lufenuron is given by mouth as a flavored chew tablet. At prescribed doses, this medication is well-tolerated; when used off-label at higher doses for treating mites, side effects have been observed. Your veterinarian will advise you on the safety of milbemycin oxime + lufenuron use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

• Milbemycin Oxime + Lufenuron + Praziquantel

  Milbemycin oxime + lufenuron + praziquantel is a heartworm disease preventive that also treats certain internal parasites and controls fleas in dogs. This combination medication is given by mouth as a flavored chew tablet. At prescribed doses, this medication is well-tolerated. Certain dog breeds are more sensitive to milbemycin than others; your veterinarian will advise you on the safety of milbemycin use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

• Milbemycin Oxime + Praziquantel

  Milbemycin oxime + praziquantel is a heartworm disease preventive that also controls tapeworms, hookworms, roundworms, and whipworms in dogs. It is given by mouth as a flavored chew tablet and must be given with a meal to ensure adequate absorption. At prescribed doses, this medication is well-tolerated. Your veterinarian will advise you on the safety of this combination product’s use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

• Milbemycin Oxime + Spinosad

  Milbemycin oxime + spinosad is a heartworm disease preventive that also controls hookworms, roundworms, whipworms, and fleas in dogs. Milbemycin oxime + spinosad is given by mouth as a flavored chew tablet. At prescribed doses, this medication is well-tolerated. Your veterinarian will advise you on the safety of this product’s use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

• Moxidectin + Imidacloprid Topical

  Moxidectin is an avermectin antiparasitic that is used to prevent heartworms and treat intestinal parasites. Imidacloprid treats and prevents fleas. These two drugs are combined in one topical product for use in cats, dogs, and ferrets. Use as directed. Side effects are uncommon and usually short-lived, however, if you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

• Moxidectin + Sarolaner + Pyrantel

  Moxidectin + sarolaner + pyrantel is a heartworm disease preventive for dogs that also treats and prevents internal parasites (hookworms and roundworms) and kills fleas and ticks. This medication is given by mouth as a flavored chew tablet. At regular doses, this medication is well-tolerated. Your veterinarian will advise you on the safety of moxidectin + sarolaner + pyrantel use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

• Preventive Healthcare Guidelines for Dogs

  The American Animal Hospital Association and American Veterinary Medical Association have established guidelines to standardize preventive health care for dogs, helping them to live longer, healthier lives. This handout provides an overview of the recommendations within these guidelines and why they are so important.